吴莹
博士,讲师,硕士生导师
个人简介
海南大学水生生物学博士,海南自由贸易港E类高层次人才,现为热带水产动物健康养殖与病害控制研究室骨干成员,承担海南省自然科学基金1项,海南大学科研启动基金项目1项,参与国家重点研发计划、国家自然科学基金等多项课题
,发表高水平学术论文10余篇。
学术成果:
长期开展卵形鲳鲹等海水鱼类免疫基因作用机制的研究,为水产病害的免疫防治提供新的策略。
1. 深入研究卵形鲳鲹干扰素调节因子家族,分析了该家族参与鱼体抗细菌免疫的功能和机制,并探索它们作为海水鱼类免疫增强剂和疫苗佐剂的应用前景。
2. 深入研究了卵形鲳鲹抗菌肽的抗菌活性及其发挥作用的关键位点,为海水鱼类病害的免疫防控提供新的思路。
3.探究了卵形鲳鲹白介素家族在抗细菌免疫反应中的作用机制。
目前研究方向主要集中在以下三方面:
1. 海水鱼类免疫系统和病害防控的研究
2. 海水鱼类免疫制剂的研发与应用
3. 海水鱼类重要病原的致病机理研究
代表性论文
1: Sun, Y.#, Cao, Z.J.#, Zhang, P.P., Wei, C.Y., Li, J.L., Wu, Y.*, Zhou, Y.C.*, IFN regulatory factor 3 of golden pompano and its NLS domain are involved in antibacterial innate immunity and regulate the expression of type I interferon (IFNa3). Frontiers In Immunology. 2023. 02. (SCI, IF=8.88)
2: Wu, Y.#, Du, H.#, Zhu, L., Zhao, N., Zhang, S., Cao, Z., Zhou, Y.*, Sun, Y.*, Bactericidal permeability-increasing protein/LPS-binding protein (BPI/LBP) enhances resistance of golden pompano Trachinotus ovatus against bacterial infection. Fish Shellfish Immunol. 2022. 10. (SCI, IF=4.80)
3: Wu, Y.#, Zhou, Y.#, Cao, Z., Chen, X., Du, H., Sun, Y.*, Interferon regulatory factor 7 contributes to the host response during Vibrio harveyi infection in the golden pompano Trachinotus ovatus. Dev Comp Immunol. 2021. 12. (SCI, IF=3.83)
4: Wu, Y.#, Zhou, Y.C.#, Cao, Z.J., Sun, Y.*, Chen, Y., Xiang, Y.J., Wang, L., Zhang, S.N., Guo, W.L., Comparative analysis of the expression patterns of IL-1β, IL-11, and IL-34 in golden pompano (Trachinotus ovatus) following different pathogens challenge. Fish & Shellfish Immunology. 2019. 08. (SCI, IF=3.298)
5: Yang, X.#, Wu, Y.#, Zhang, P., Chen, G., Cao, Z., Ao, J., Sun, Y.*, Zhou, Y.*, CC chemokine 1 protein from Cromileptes altivelis (CaCC1) promotes antimicrobial immune defense. Fish Shellfish Immunol. 2022. 02. (SCI, IF=4.80)
6: Chen, X.#, Wu, Y.#, Qiu, Y., Li, P., Cao, Z., Zhou, Y.*, Sun, Y.*, CpG ODN 2102 promotes antibacterial immune responses and enhances vaccine-induced protection in golden pompano (Trachinotus ovatus). Fish Shellfish Immunol. 2023. 04. (SCI, IF=4.80)
招生专业
渔业发展专业硕士
联系方式
电子邮箱:wuying0947009@126.com