邓恒为
博士，副教授、博士生导师
个人简介
中山大学理学博士、博士后，海南自贸港D类人才，中国-东盟海水养殖技术“一带一路”联合实验室国际合作科技特派员，曾任海南省农业农村厅发展规划处四级调研员（挂职1年）。主要从事海洋动物分子免疫学及海洋生物病原分子生物学的研究。主持国家自然科学基金2项、农业农村部农业产业融合发展项目1项、广东省自然科学基金1项、海南大学启动基金1项及福建省重点实验室开发课题1项，参与多项国家自然科学基金项目。发表论文30篇，其中SCI论文25篇，申请专利2项。
研究方向
1. 甲壳动物抗病毒免疫分子机制
2. 水生动物先天性免疫调控机制
3. 病毒功能基因、致病机理及其与宿主的相互作用
研究项目
1. 国自然地区科学基金，32260924，拟穴青蟹SOCS2介导的JAK/STAT通路负反馈环路及其对机体免疫稳态调控的分子机制，2023/01-2026/12，主持
2. 国自然青年科学基金，32002440，拟穴青蟹干扰素调节因子调控干扰素诱导基因ISG12抗病毒的分子机制，2021/01-2023/12，主持
3. 农业农村部农业产业融合发展项目，对虾种资资源引进中转示范基地，2024/06-2026/09，主持
4. 广东省自然科学基金面上项目，2022A1515010958，拟穴青蟹SOCS2负反馈调控JAK/STAT通路参与抗病毒免疫反应，2022/01-2024/12，主持
5. 海南大学科研启动项目，拟穴青蟹干扰素诱导基因IFI27L2抗病毒的分子机制，2022/02-2027/02，主持
6. 水产动物疫病防控与健康养殖全国重点实验室开放课题，2024SKLBC-KF04，黄芩苷通过抑制β-溶血活性防控无乳链球菌的机制研究，2025/01-2026/12，主持
7. 福建省海洋渔业资源与生态环境重点实验室课题，JAK-STAT通路调控拟穴青蟹免疫稳态的分子机制及抗病毒效应，2023/10-2025/10，主持
8. 国家自然科学基金面上项目，32073004，p38 MAPK信号通路调控凡纳滨对虾血淋巴透明细胞吞噬功能活化的分子机制，2021/01-2024/12，参与
代表论文
1. Hengwei Deng, Yetong Ke, Shaoping Weng, Lei Hu, Wenfeng Zhang, Yujia Sun, Linwei Yang, Xuewen Wang, Mingyang Feng, Weiliang Guo, Zhihong Zhong, Dongdong Zhang, Jianguo He*, Yongcan Zhou*, A cytokine receptor domeless restrains mud crab reovirus infection via JAK-STAT signaling pathway in mud crab (Scylla paramamosain), Fish & Shellfish Immunology, 163(2025)110402.
2. Hengwei Deng, Danrong Xian, Taixin Lian, Mingyu He, Jingjing Li, Xiaopeng Xu, Zhixun Guo, Jianguo He*, Shaoping Weng*, A Dicer2 from Scylla paramamosain activates JAK/STAT signaling pathway to restrain mud crab reovirus, Developmental and Comparative Immunology, 127(2022)104267.
3. Hengwei Deng, Yeyu Li, Jinling Li, Wenjie Shen, Qiankang Chen, Shaoping Weng, Jianguo He, Xiaopeng Xu*, Neomycin inhibits Megalocytivirus infection in fish by antagonizing the increase of intracellular reduced glutathione, Fish & Shellfish Immunology, 127(2022), 148-154.
4. Hengwei Deng, Lei Hu, Jingjing Li, Wenyan Yan, Enhui Song, Mingqing Kuang, Shanshan Liu, Jianguo He*, Shaoping Weng*, The NF-κB family member dorsal plays a role in immune response against Gram-positive bacterial infection in mud crab (Scylla paramamosain), Developmental and Comparative Immunology,106 (2020) 103581.
5. Hengwei Deng, Wenfeng Zhang, Jingjing Li, Jinling Li, Lei Hu, Wenyan Yan, Shanshan Liu, Jianguo He*, Shaoping Weng*, A signal transducers and activators of transcription (STAT) gene from Scylla paramamosain is involved in resistance against mud crab reovirus, Fish & Shellfish Immunology,94 (2019) 580-591.
6. Hengwei Deng, Xiaopeng Xu, Lei Hu, Jingjing Li, Dandan Zhou, Shanshan Liu, Panpan Luo, Jianguo He*, Shaoping Weng*, A janus kinase from Scylla paramamosain activates JAK/STAT signaling pathway to restrain mud crab reovirus, Fish & Shellfish Immunology,90 (2019) 275-287.
7. Deng Hengwei, Li Zhongbao*, Dai Gang, Yuan Yi, Ning Yefeng, Shangguan Jingbo, Huang Yesheng. Isolation of new polymorphic microsatellite markers from the marbled rockfish Sebastiscus marmoratus. Genetics and molecular research, 14(2015): 758-762.
8. Wei-Liang Guo, Heng-Wei Deng, Fei Wang, Shi-Feng Wang, Zhi-Hong Zhong, Yun Sun, Xue-Fen Chen, Jin-Hua Wang, Yong-Can Zhou*. In vitro and in vivo screening of herbal extracts against Streptococcus agalactiae in Nile tilapia (Oreochromis niloticus). Aquaculture, 503 (2019) 412-421.
9. Wenfeng Zhang, Hengwei Deng, Yuting Fu, Weixuan Fu, Shaoping Weng, Jianguo He, Chuanfu Dong*. Production and characterization of monoclonal antibodies against mandarinfish ranavirus and first identification of pyloric caecum as the major target tissue. Journal of Fish Diseases, 0(2022), 1-11.
10.Linwei Yang, Yushi Gan, Hengwei Deng, Jianguo He*, Xiaopeng Xu*. Recent Research Advances on the Hippo‐Yki Pathway of Crustaceans: Current Knowledge and Potential Applications in Crustacean Aquaculture. Reviews in Aquaculture. 2025, 17: e12955
11. Long Zhang, Kun Wu, Haoyang Li, Minwen Zhan, Sheng Wang, Enhui Song, Jian He, Xinyi He, Menghuang Xu, Hengwei Deng, Yingchun Su, Ziwei Liu, Zhuyue Yan, Zhuyue Yan, Peipei Tan, Mengyun He, Shaoping Weng, Wei Ge, Jianguo He*, Muhua Wang*.Vitellogenin receptor mediates heat adaptability of oocyte development in mud crabs and zebrafish. Nature Communications, 16(2025): 3722.
12. Jiefeng Gao#, Ran Geng#, Hengwei Deng, Hongliang Zuo, Shaoping Weng, Jianguo He*, Xiaopeng Xu*. A novel Forkhead box protein P (FoxP) from Litopenaeus vannamei plays a positive role in immune response. Frontiers in Immunology, 11(2020):593987.
13. Linwei Yang, Ziang Wang, Ran Geng, Hengwei Deng, Shengwen Niu, Hongliang Zuo, Shaoping Weng, Jianguo He, Xiaopeng Xu. White Spot Syndrome Virus (WSSV) Inhibits Hippo Signaling and Activates Yki to Promote Its Infection in Penaeus vannamei. Microbiol Spectr, 11(2023):0236322.
14. Jian-Hui He, Wenjie Shen, Deyu Han, Muting Yan, Mengting Luo, Hengwei Deng, Shaoping Weng, Jianguo He, Xiaopeng Xu. Molecular mechanism of the interaction between Megalocytivirus-induced virus-mock basement membrane (VMBM) and lymphatic endothelial cells. Journal of Virology, 97(2023):0048023.
招生专业
水产（学术博士）、水产养殖学（学术硕士）、渔业发展（专业硕士）。欢迎同学们积极联系报考。
联系方式
电子邮箱：hengweideng@163.com
